Details
Product Description
Product Name | Ciprofloxacin HCl |
CAS | 86393-32-0 |
MF | C17H21ClFN3O4 |
MW | 385.82 |
Application | Fluorinated quinolone antibacterial |
Introduction | Ciprofloxacin is an antibiotic used to treat a number of bacterial infections.This includes bone and joint infections, intra abdominal infections, certain type of infectious diarrhea, respiratory tract infections, skin infections, typhoid fever, and urinary tract infections, among others. For some infections it is used in addition to other antibiotics.It can be taken by mouth or used intravenously. |
BP/USP pharmaceutical grade Ciprofloxacin Hcl/Ciprofloxacin Hcl powder.
ANALYSIS AS PER USP 34
Items of Test | Standard | Result of Test |
Appearance | White or light yellow crystalline powder | conform |
Identification | ||
(a) IR | IR spectrum of sample corresponds to that of reference standard. | Conform |
The intensity and RF value of the principal band obtained from the test solution corresponds to that obtained from the standard solution. | ||
(b) TLC | A solution of IIresponds to the tests of chloride | Conform |
(c) the reaction of chloride | Conform | |
Related substances HPLC | Chromatographic purity ≤ 0.2% | 0.15% |
Ciprofloxacin ethylenediamine analog ≤ 0.2% | <0.11% | |
Unspecified impurity ≤ 0.50% | 0.40% | |
Total impurities ≤ 0.5% | ||
Ph | 3.0-4.5 | 3.7 |
Heavy metals | ≤20ppm | <20ppm |
Fluoroquinolonic acid | ≤0.2% | Conform |
Sulphated ash | ≤0.04% | <0.04% |
Water | 4.7%-6.7% | 5.90% |
Residue of ignition | ≤0.1% | 0.05% |
Residual solvent | ethanol ≤ 5000ppm | 560ppm |
Isoamyl alcohol≤ 4000ppm | Not found | |
Assay (HPLC) | 98.0%-102% | 99.80% |
